Services Ockie Fourie Toxicologists (OFT) are independent toxicologists, which provide a wide range of services. We provide product safety assessments through toxicological risk assessments to human health and the environment, potential risk calculations for management decision making in remediation options, product registration submissions, classification and labeling according to the latest global directives, and many more, some of which are indicated below.
Toxicological dossiers, when prepared by multi-national companies to obtain registration for a particular product, is reviewed, human health and environmental risk assessments performed, and summary reports prepared for submission to Regulatory Authorities. Product safety assessments Guidance is provided to clientele in the agricultural, pharmaceutical and chemical industries on the safety and potential risk of a product to the consumer, worker, the general public and to the environment at large. Toxicological data is evaluated with regard to inter alia active and inactive ingredients, impurities and metabolites, taking in consideration the proposed methods of use and application. Ockie Fourie Toxicologists recognizes that when safety to any form of life is the objective, the only rational approach is through the nature of the toxicity in question, and the application of benefits versus potential hazards under the condition of intended use of the compound. Toxicological and pre-clinical protocols Ockie Fourie Toxicologists have vast experience in studies required to allow safety assessments and the calculation of potential risk to human health and the environment, utilizing surrogates and indicator organisms. Tiered approaches are used and recommended, based on sound scientific and toxicological practices to satisfy regulatory requirements, whilst protocols adhere to GLP.
The mere presence of a chemical substance does not ipso facto imply a detrimental effect. At OFT we quantify actual or potential risk to the environment and human health by primary and secondary sources. OFT also classifies the quantified risk in order to allow managers and regulatory bodies to formulate applicable remediation measures, preventing over-regulation, under-regulation and hence costs to industry. Hazardous waste disposal We classify hazardous waste to be disposed of by landfill, and recommend landfill and treatment options according to potential risk due to the composition, nature and volume of waste. Globally harmonized system of classification and labelling of chemicals (GHS) OFT, in agreement with the goal of the GHS, renders a service to industry by identification of the intrinsic hazards of products and chemical substances, to apply hazard classification and labelling according to the globally harmonized criteria and hazard communication elements as formulated by GHS. Services not specifically mentioned Regulatory, environmental, clinical and ecological toxicology are disciplines, which provide guidance on matters related to human health and the environment. In agreement with our mission to enhance quality of life, assist industry on health and safety matters and promote and enhance environmental well-being, we provide expertise for all matters, which could achieve, promote and enhance quality of life. The mere PRESENCE of a chemical substance does not ipso facto imply a detrimental effect |
Peer review of toxicological dossiers 
Remediation of contaminated land